en پزشکی عمومى General medicine تحقیقی Original article <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Times New Roman;"><b>Background:</b> End-Stage Renal Disease (ESRD) patients under maintenance hemodialysis are at higher risk for COVID-19 and severe outcomes. This study aimed to investigate the association between ESRD patients who underwent maintenance hemodialysis at 5th Azar and Sayad Shirazi Hospital in Golestan Province in 2019 and their risk of acquiring and experiencing severe outcomes from COVID-19. Furthermore, this study aimed to provide insights into the epidemic status of COVID-19 in this specific population, contributing to better insight into the unique challenges faced by ESRD patients on hemodialysis during the pandemic.<br> <b>Methods:</b> This retrospective descriptive cross-sectional study was performed on patients who underwent maintenance hemodialysis. The diagnosis was made based on diagnostic criteria and COVID-19 PCR test. Medical information of all participants was collected. Medical information including clinical, laboratory, and radiological data as well as morbidity and mortality were collected and analyzed by experts. Statistical analysis was performed using SPSS version 21. Normality was evaluated using Shapiro-Wilk test and comparison between groups was analyzed using student T-test and Mann-Whitney U tests (P-Value < 0.05).<br> <b>Results:</b> The most prevalent radiological findings were ground glass opacities, observed in 46.7% of cases, followed by linear opacities, noted in 26.7% of cases. Most patients (86.6%) were discharged and four of them (13.4%) passed away. WBC, serum creatinine, and age were significantly associated with ESRD patients&rsquo; mortality (P-Value < 0.05). The patients who passed away were old and had higher levels of WBC and creatinine (P-Value > 0.05). No significant difference was observed between the age and BMI of passed away and discharged patients. None of the other laboratory parameters in the two groups of passed away and discharged patients with COVID-19 showed a significant difference (P-Value > 0.05). <b><span style="font-size:8.0pt"></span></b><br> <b>Conclusion</b>: ESRD patients who underwent hemodialysis due to their underlying problems and the crowded environment of dialysis wards more than the general population are at risk of getting COVID-19.</span></span></div> Kidney Failure, Chronic, COVID-19, Mortality, Leukocyte Count, Creatinine, Hemodialysis 18 21 http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-964-1&slc_lang=en&sid=1 Samira Juibari samira.com1360@gmail.com 100319475328460010589 100319475328460010589 No Clinical Research Development Unit (CRDU), Sayyad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran Anna Rashedi anna-rashedi@yahoo.com 100319475328460010590 100319475328460010590 No Clinical Research Development Unit (CRDU), Sayyad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran Mohammad Mojerloo moujerloo@yahoo.com 100319475328460010591 0009-0002-0692-9753 No Department of Hemodialysis, 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran Zeinab Mohammadi mohammadi.ac64@gmail.com 100319475328460010592 100319475328460010592 No Metabolic Disorders Research Center, Golestan University of Medical Sciences, Golestan, Iran Saeid Amirkhanlou drsam74ir@ymail.com 100319475328460010593 100319475328460010593 Yes Clinical Research Development Unit (CRDU), Sayyad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran